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Nonclassical MHC Ib-restricted CD8(+) T Cells Recognize Mycobacterium tuberculosis-Derived Protein Antigens and Contribute to Protection Against Infection

MHC Ib-restricted CD8(+) T cells have been implicated in host defense against Mycobacterium tuberculosis (Mtb) infection. However, the relative contribution of various MHC Ib-restricted T cell populations to anti-mycobacterial immunity remains elusive. In this study, we used mice that lack MHC Ia (K...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Shang, Shaobin, Siddiqui, Sarah, Bian, Yao, Zhao, Jie, Wang, Chyung-Ru
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896622/
https://ncbi.nlm.nih.gov/pubmed/27272249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005688
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