Serum microRNA signatures as "liquid biopsies" for interrogating hepatotoxic mechanisms and liver pathogenesis in human

MicroRNAs (miRNAs) released into the peripheral circulation upon cellular injury have shown a promise as a new class of tissue-specific biomarkers. We were first to demonstrate that next-generation sequencing analysis of serum from human subjects with acetaminophen-induced liver injury revealed a sp...

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Publicado en:PLoS One
Autores principales: Krauskopf, Julian, de Kok, Theo M., Schomaker, Shelli J., Gosink, Mark, Burt, Deborah A., Chandler, Patricia, Warner, Roscoe L., Johnson, Kent J., Caiment, Florian, Kleinjans, Jos C., Aubrecht, Jiri
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5435338/
https://ncbi.nlm.nih.gov/pubmed/28545106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177928
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