Tetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM

The natural small molecule compound: 2,3,5,6-tetramethylpyrazine (TMP), is a major component of the Chinese medicine Chuanxiong, which has wide clinical applications in dilating blood vessels, inhibiting platelet aggregation and treating thrombosis. Recent work suggests that TMP is also an antitumou...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Lan, Linhua, Guo, Miaomiao, Ai, Yong, Chen, Fuhong, Zhang, Ya, Xia, Lei, Huang, Dawei, Niu, Lili, Zheng, Ying, Suzuki, Carolyn K., Zhang, Yihua, Liu, Yongzhang, Lu, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434891/
https://ncbi.nlm.nih.gov/pubmed/28465355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170319
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