Tetramethylpyrazine blocks TFAM degradation and up-regulates mitochondrial DNA copy number by interacting with TFAM

The natural small molecule compound: 2,3,5,6-tetramethylpyrazine (TMP), is a major component of the Chinese medicine Chuanxiong, which has wide clinical applications in dilating blood vessels, inhibiting platelet aggregation and treating thrombosis. Recent work suggests that TMP is also an antitumou...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biosci Rep
Prif Awduron: Lan, Linhua, Guo, Miaomiao, Ai, Yong, Chen, Fuhong, Zhang, Ya, Xia, Lei, Huang, Dawei, Niu, Lili, Zheng, Ying, Suzuki, Carolyn K., Zhang, Yihua, Liu, Yongzhang, Lu, Bin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Portland Press Ltd. 2017
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434891/
https://ncbi.nlm.nih.gov/pubmed/28465355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170319
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