ROG Negatively Regulates T-Cell Activation but Is Dispensable for Th-Cell Differentiation

ROG, a transcriptional repressor, is a direct target gene of NF-AT and a putative negative regulator of T-cell activation. In addition, overexpression of ROG suppresses the activity of GATA-3, implying a role of ROG in the differentiation and function of Th cells. Despite these observations, the fun...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Kang, Bok Yun, Miaw, Shi-Chuen, Ho, I-Cheng
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2005
Assuntos:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC543427/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15632058/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.2.554-562.2005
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