ROG Negatively Regulates T-Cell Activation but Is Dispensable for Th-Cell Differentiation

ROG, a transcriptional repressor, is a direct target gene of NF-AT and a putative negative regulator of T-cell activation. In addition, overexpression of ROG suppresses the activity of GATA-3, implying a role of ROG in the differentiation and function of Th cells. Despite these observations, the fun...

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Detalhes bibliográficos
Main Authors: Kang, Bok Yun, Miaw, Shi-Chuen, Ho, I-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC543427/
https://ncbi.nlm.nih.gov/pubmed/15632058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.2.554-562.2005
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