BRCTx Is a Novel, Highly Conserved RAD18-Interacting Protein

The BRCT domain is a highly conserved module found in many proteins that participate in DNA damage checkpoint regulation, DNA repair, and cell cycle control. Here we describe the cloning, characterization, and targeted mutagenesis of Brctx, a novel gene with a BRCT motif. Brctx was found to be expre...

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Bibliographic Details
Main Authors: Adams, David J., van der Weyden, Louise, Gergely, Fanni V., Arends, Mark J., Ng, Bee Ling, Tannahill, David, Kanaar, Roland, Markus, Andrea, Morris, Brian J., Bradley, Allan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC543416/
https://ncbi.nlm.nih.gov/pubmed/15632077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.2.779-788.2005
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