Time to Amyloid Positivity and Preclinical Changes in Brain Metabolism, Atrophy, and Cognition: Evidence for Emerging Amyloid Pathology in Alzheimer's Disease

Background: Aβ pathology is associated with longitudinal changes of brain metabolism, atrophy, and cognition, in cognitively healthy elders. However, Aβ information is usually measured cross-sectionally and dichotomized to classify subjects as Aβ-positive or Aβ-negative, making it difficult to evalu...

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Vydáno v:Front Neurosci
Hlavní autoři: Insel, Philip S., Ossenkoppele, Rik, Gessert, Devon, Jagust, William, Landau, Susan, Hansson, Oskar, Weiner, Michael W., Mattsson, Niklas
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434146/
https://ncbi.nlm.nih.gov/pubmed/28567001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2017.00281
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