Regulation of p53 and MDM2 Activity by MTBP
p53 is a critical coordinator of a wide range of stress responses. To facilitate a rapid response to stress, p53 is produced constitutively but is negatively regulated by MDM2. MDM2 can inhibit p53 in multiple independent ways: by binding to its transcription activation domain, inhibiting p53 acetyl...
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| Udgivet i: | Mol Cell Biol |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Taylor & Francis
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC543405/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15632057/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.25.2.545-553.2005 |
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