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Regulation of p53 and MDM2 Activity by MTBP
p53 is a critical coordinator of a wide range of stress responses. To facilitate a rapid response to stress, p53 is produced constitutively but is negatively regulated by MDM2. MDM2 can inhibit p53 in multiple independent ways: by binding to its transcription activation domain, inhibiting p53 acetyl...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2005
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC543405/ https://ncbi.nlm.nih.gov/pubmed/15632057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.2.545-553.2005 |
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