Human Protection of Telomeres 1 (POT1) Is a Negative Regulator of Telomerase Activity In Vitro

The telomeric single-strand DNA binding protein protection of telomeres 1 (POT1) protects telomeres from rapid degradation in Schizosaccharomyces pombe and has been implicated in positive and negative telomere length regulation in humans. Human POT1 appears to interact with telomeres both through di...

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Bibliographic Details
Main Authors: Kelleher, Colleen, Kurth, Isabel, Lingner, Joachim
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Chromosome Structure and Dynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC543404/
https://ncbi.nlm.nih.gov/pubmed/15632080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.2.808-818.2005
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