Rationalized design of a mucosal vaccine protects against Mycobacterium tuberculosis challenge in mice

Pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is a leading cause of global morbidity and mortality. The only licensed TB vaccine, Mycobacterium bovis bacillus Calmette-Guerin (BCG), has variable efficacy in protecting against pulmonary TB. Thus, the development of more effec...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Leukoc Biol
Auteurs principaux: Ahmed, Mushtaq, Jiao, Hongmei, Domingo-Gonzalez, Racquel, Das, Shibali, Griffiths, Kristin L., Rangel-Moreno, Javier, Nagarajan, Uma M., Khader, Shabaana A.
Format: Artigo
Langue:Inglês
Publié: Society for Leukocyte Biology 2017
Sujets:
Host Defense & Pathophysiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433857/
https://ncbi.nlm.nih.gov/pubmed/28258153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.4A0616-270R
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