ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which upper and lower motoneurons degenerate leading to muscle wasting, paralysis and eventually death from respiratory failure. Several studies indicate that skeletal muscle contributes to disease progression; however the m...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Gonzalez, David, Contreras, Osvaldo, Rebolledo, Daniela L., Espinoza, Juan Pablo, van Zundert, Brigitte, Brandan, Enrique
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433732/
https://ncbi.nlm.nih.gov/pubmed/28520806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177649
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