ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which upper and lower motoneurons degenerate leading to muscle wasting, paralysis and eventually death from respiratory failure. Several studies indicate that skeletal muscle contributes to disease progression; however the m...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Gonzalez, David, Contreras, Osvaldo, Rebolledo, Daniela L., Espinoza, Juan Pablo, van Zundert, Brigitte, Brandan, Enrique
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433732/
https://ncbi.nlm.nih.gov/pubmed/28520806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177649
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