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Safety, tolerability and pharmacodynamics of a novel immunomodulator, MIS416, in patients with chronic progressive multiple sclerosis

BACKGROUND: Preclinical studies have demonstrated that MIS416, a bacterially derived immune modulator, targets myeloid cells following systemic delivery. MIS416 stimulated myeloid cells have the capacity to regulate innate inflammation, a potential therapeutic target for progressive multiple scleros...

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Detalhes bibliográficos
Publicado no:Mult Scler J Exp Transl Clin
Main Authors: Luckey, Alison M, Anderson, Tim, Silverman, Michael H, Webster, Gill
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433401/
https://ncbi.nlm.nih.gov/pubmed/28607691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2055217315583385
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