Targeting Innate Receptors with MIS416 Reshapes Th Responses and Suppresses CNS Disease in a Mouse Model of Multiple Sclerosis

Modification of the innate immune cell environment has recently been recognized as a viable treatment strategy for reducing autoimmune disease pathology. MIS416 is a microparticulate immune response modifier that targets myeloid cells, activating cytosolic receptors NOD2 and TLR9, and has completed...

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Detalhes bibliográficos
Main Authors: White, Madeleine, Webster, Gill, O’Sullivan, David, Stone, Sarrabeth, La Flamme, Anne Camille
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909208/
https://ncbi.nlm.nih.gov/pubmed/24498172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087712
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