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Antagonistic action on NMDA/GluN2B mediated currents of two peptides that were conantokin-G structure-based designed

BACKGROUND: The GluN2B subunit of the N-methyl-d-aspartate receptor (NMDAr) modulates many physiological processes including learning, memory, and pain. Excessive increase in NMDAr/GluN2B activity has been associated with various disorders such neuropathic pain and neuronal death following hypoxia....

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Foilsithe in:BMC Neurosci
Main Authors: Reyes-Guzman, Edwin A., Vega-Castro, Nohora, Reyes-Montaño, Edgar A., Recio-Pinto, Esperanza
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5433008/
https://ncbi.nlm.nih.gov/pubmed/28511693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0361-4
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