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Antagonistic action on NMDA/GluN2B mediated currents of two peptides that were conantokin-G structure-based designed
BACKGROUND: The GluN2B subunit of the N-methyl-d-aspartate receptor (NMDAr) modulates many physiological processes including learning, memory, and pain. Excessive increase in NMDAr/GluN2B activity has been associated with various disorders such neuropathic pain and neuronal death following hypoxia....
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| Publicado no: | BMC Neurosci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5433008/ https://ncbi.nlm.nih.gov/pubmed/28511693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0361-4 |
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