A Single-Dose Recombinant Parainfluenza Virus 5-Vectored Vaccine Expressing Respiratory Syncytial Virus (RSV) F or G Protein Protected Cotton Rats and African Green Monkeys from RSV Challenge

Human respiratory syncytial virus (RSV) is a common cause of severe respiratory disease among infants, immunocompromised individuals, and the elderly. No licensed vaccine is currently available. In this study, we evaluated two parainfluenza virus 5 (PIV5)-vectored vaccines expressing RSV F (PIV5/F)...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Wang, Dai, Phan, Shannon, DiStefano, Daniel J., Citron, Michael P., Callahan, Cheryl L., Indrawati, Lani, Dubey, Sheri A., Heidecker, Gwendolyn J., Govindarajan, Dhanasekaran, Liang, Xiaoping, He, Biao, Espeseth, Amy S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432884/
https://ncbi.nlm.nih.gov/pubmed/28298602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00066-17
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