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Human Herpesvirus 6B Induces Hypomethylation on Chromosome 17p13.3, Correlating with Increased Gene Expression and Virus Integration

Human herpesvirus 6B (HHV-6B) is a neurotropic betaherpesvirus that achieves latency by integrating its genome into host cell chromosomes. Several viruses can induce epigenetic modifications in their host cells, but no study has investigated the epigenetic modifications induced by HHV-6B. This study...

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Publicado en:J Virol
Main Authors: Engdahl, Elin, Dunn, Nicky, Niehusmann, Pitt, Wideman, Sarah, Wipfler, Peter, Becker, Albert J., Ekström, Tomas J., Almgren, Malin, Fogdell-Hahn, Anna
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432873/
https://ncbi.nlm.nih.gov/pubmed/28298607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02105-16
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