Human Herpesvirus 6B Induces Hypomethylation on Chromosome 17p13.3, Correlating with Increased Gene Expression and Virus Integration

Human herpesvirus 6B (HHV-6B) is a neurotropic betaherpesvirus that achieves latency by integrating its genome into host cell chromosomes. Several viruses can induce epigenetic modifications in their host cells, but no study has investigated the epigenetic modifications induced by HHV-6B. This study...

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Publicat a:J Virol
Autors principals: Engdahl, Elin, Dunn, Nicky, Niehusmann, Pitt, Wideman, Sarah, Wipfler, Peter, Becker, Albert J., Ekström, Tomas J., Almgren, Malin, Fogdell-Hahn, Anna
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Virus-Cell Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432873/
https://ncbi.nlm.nih.gov/pubmed/28298607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02105-16
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