Human Herpesvirus 6B Induces Hypomethylation on Chromosome 17p13.3, Correlating with Increased Gene Expression and Virus Integration

Human herpesvirus 6B (HHV-6B) is a neurotropic betaherpesvirus that achieves latency by integrating its genome into host cell chromosomes. Several viruses can induce epigenetic modifications in their host cells, but no study has investigated the epigenetic modifications induced by HHV-6B. This study...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Engdahl, Elin, Dunn, Nicky, Niehusmann, Pitt, Wideman, Sarah, Wipfler, Peter, Becker, Albert J., Ekström, Tomas J., Almgren, Malin, Fogdell-Hahn, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432873/
https://ncbi.nlm.nih.gov/pubmed/28298607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02105-16
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