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Genetic analysis of age at onset variation in spinocerebellar ataxia type 2

OBJECTIVE: To examine heritability of the residual variability of spinocerebellar ataxia type 2 (SCA2) age at onset (AO) after controlling for CAG repeat length. METHODS: From 1955 to 2001, dates of birth, CAG repeat lengths, AO, sex, familial inheritances, and clinical manifestations were collected...

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Bibliografske podrobnosti
izdano v:Neurol Genet
Main Authors: Figueroa, K.P., Coon, Hilary, Santos, Nieves, Velazquez, Luis, Mederos, Luis Almaguer, Pulst, Stefan M.
Format: Artigo
Jezik:Inglês
Izdano: Wolters Kluwer 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432368/
https://ncbi.nlm.nih.gov/pubmed/28534046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXG.0000000000000155
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