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Gambogic acid suppresses cancer invasion and migration by inhibiting TGFβ1-induced epithelial-to-mesenchymal transition

The epithelial-to-mesenchymal transition (EMT) contributes to the disruption of cell–cell junctions and imbues cancer cells with invasive and migratory properties. In this study, we investigated the effect of gambogic acid, a xanthone extracted from the resin of Garciania hanburyi, on transforming g...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Zhao, Kai, Zhang, Shuai, Song, Xiuming, Yao, Yuyuan, Zhou, Yuxin, You, Qidong, Guo, Qinglong, Lu, Na
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432322/
https://ncbi.nlm.nih.gov/pubmed/28404892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15449
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