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The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm

Vitamin D has pleiotropic effects on multiple tissues, including malignant tumors. Vitamin D inhibits breast cancer growth through activation of the vitamin D receptor (VDR) and via classical nuclear signaling pathways. Here, we demonstrate that the VDR can also function in the absence of its ligand...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Trivedi, Trupti, Zheng, Yu, Fournier, Pierrick G.J., Murthy, Sreemala, John, Sutha, Schillo, Suzanne, Dunstan, Colin R., Mohammad, Khalid S., Zhou, Hong, Seibel, Markus J., Guise, Theresa A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432290/
https://ncbi.nlm.nih.gov/pubmed/28460457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15803
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