Trichosanthin increases Granzyme B penetration into tumor cells by upregulation of CI-MPR on the cell surface

Trichosanthin is a plant toxin belonging to the family of ribosome-inactivating proteins. It has various biological and pharmacological activities, including anti-tumor and immunoregulatory effects. In this study, we explored the potential medicinal applications of trichosanthin in cancer immunother...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Li, Chunman, Zeng, Meiqi, Chi, Huju, Shen, Jing, Ng, Tzi-Bun, Jin, Guangyi, Lu, Desheng, Fan, Xinmin, Xiong, Bilian, Xiao, Zhangang, Sha, Ou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432272/
https://ncbi.nlm.nih.gov/pubmed/28460437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15518
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