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A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking

The cation-independent mannose-6-phosphate receptor (CI-MPR) follows a highly regulated sorting itinerary to deliver hydrolases from the trans-Golgi network (TGN) to lysosomes. Cycling of CI-MPR between the TGN and early endosomes is mediated by GGA3, which directs TGN export, and PACS-1, which dire...

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Detalhes bibliográficos
Main Authors: Scott, Gregory K, Fei, Hao, Thomas, Laurel, Medigeshi, Guruprasad R, Thomas, Gary
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1589982/
https://ncbi.nlm.nih.gov/pubmed/16977309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601336
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