Promoter mutations and cellular distribution of telomerase in non-clear cell and clear cell hepatocellular carcinoma

Reactivation of telomerase is a critical step in the development of hepatocellular carcinoma (HCC). Here we identified the frequency of mutations in telomerase reverse transcriptase (TERT) promoter was 34% in non-clear cell HCC (NCCHCC, n = 259) and 26.3% in clear cell HCC (CCHCC, n = 57). The mutat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Huang, Wan, Zhou, Weiping, Li, Can, Yang, Yuan, Shang, Yu-Kui, Chen, Changsheng, Zhang, Jing, Yao, Rui, Wang, Pei, Wen, Wen, Liu, Han-Qiang, Wang, Ling, Li, Xia, Bian, Huijie, Chen, Zhi-Nan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432257/
https://ncbi.nlm.nih.gov/pubmed/28460432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15458
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