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Extracellular matrix nitration alters growth factor release and activates bioactive complement in human retinal pigment epithelial cells
PURPOSE: We have shown previously that non-enzymatic nitration (NEN) of the extracellular matrix (ECM), which serves as a model of Bruch’s membrane (BM) aging, has a profound effect on the behavior of the overlying retinal pigment epithelial (RPE) cells, including altered phagocytic ability, reduced...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5432172/ https://ncbi.nlm.nih.gov/pubmed/28505174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177763 |
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