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DIFFERENTIAL DISTRIBUTION AND FUNCTIONAL IMPACT OF BK CHANNEL BETA1 SUBUNITS ACROSS MESENTERIC, CORONARY AND DIFFERENT CEREBRAL ARTERIES OF THE RAT

Large conductance, Ca(2+)(i)- and voltage-gated K(+) (BK) channels regulate myogenic tone and thus, arterial diameter. In smooth muscle (SM), BK channels include channel-forming α and auxiliary β1 subunits. BK β1 increases the channel’s Ca(2+) sensitivity allowing BK channels to negatively feed-back...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Pflugers Arch
Hauptverfasser: Kuntamallappanavar, Guruprasad, Bisen, Shivantika, Bukiya, Anna N., Dopico, Alex M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432129/
https://ncbi.nlm.nih.gov/pubmed/28012000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1929-z
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