Autocrine transformation by chimeric signal peptide-basic fibroblast growth factor: reversal by suramin.
NIH 3T3 cells transfected with basic fibroblast growth factor (bFGF) fused to an immunoglobulin signal peptide sequence are transformed in vitro and tumorigenic in vivo. The transformed phenotype of chimeric signal peptide-bFGF (spbFGF) cells is characterized by an enhanced proliferation rate compar...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54320/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2164679/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.14.5346 |
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