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Autocrine transformation by chimeric signal peptide-basic fibroblast growth factor: reversal by suramin.

NIH 3T3 cells transfected with basic fibroblast growth factor (bFGF) fused to an immunoglobulin signal peptide sequence are transformed in vitro and tumorigenic in vivo. The transformed phenotype of chimeric signal peptide-bFGF (spbFGF) cells is characterized by an enhanced proliferation rate compar...

詳細記述

保存先:
書誌詳細
主要な著者: Yayon, A, Klagsbrun, M
フォーマット: Artigo
言語:Inglês
出版事項: 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC54320/
https://ncbi.nlm.nih.gov/pubmed/2164679
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