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Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62
ES-62, a glycoprotein secreted by the parasitic filarial nematode Acanthocheilonema viteae, subverts host immune responses towards anti-inflammatory phenotypes by virtue of covalently attached phosphorylcholine (PC). The PC dictates that ES-62 exhibits protection in murine models of inflammatory dis...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431997/ https://ncbi.nlm.nih.gov/pubmed/28490801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01651-1 |
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