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Artificial disulfide-rich peptide scaffolds with precisely defined disulfide patterns and a minimized number of isomers
Disulfide-rich peptides are emerging as potential templates for drug design applications. However, the synthesis and reengineering of disulfide-rich peptides are challenging, owing to the complexity of the oxidative folding process involving a number of diverse isomeric structures. Novel disulfide-r...
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| Veröffentlicht in: | Chem Sci |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Royal Society of Chemistry
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431680/ https://ncbi.nlm.nih.gov/pubmed/28553486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc05710a |
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