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Molecular mechanisms underlying the evolution of the slp76 signalosome

The well-defined mammalian slp76-signalosome is crucial for T-cell immune response, yet whether slp76-signalosome exists in invertebrates and how it evolved remain unknown. Here we investigated slp76-signalosome from an evolutionary perspective in amphioxus Branchiostoma belcheri (bb). We proved slp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Qu, Xuemei, Lan, Xin, Deng, Chong, Zhou, Jiatao, Du, Jingjing, Huang, Shengfeng, Li, Yingqiu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431462/
https://ncbi.nlm.nih.gov/pubmed/28473706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01660-0
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