A 2-oxa-spiro[5.4]decane scaffold displays neurotrophic, neurogenic and anti-neuroinflammatory activities with high potential for development as a versatile CNS therapeutic

Following our recent discovery of a new scaffold exhibiting significant neurotrophic and neurogenic activities, a structurally tweaked analogue, embodying a 2-oxa-spiro [5.4]decane framework, has been conceptualised and found to be more potent and versatile. It exhibits enhanced neurotrophic and neu...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Joshi, Pranav Chintamani, Samineni, Ramesh, Bhattacharya, Dwaipayan, Reddy, Bommana Raghunath, Veeraval, Lenin, Das, Tapatee, Maitra, Swati, Wahul, Abhipradnya Bipin, Karri, Shailaja, Pabbaraja, Srihari, Mehta, Goverdhan, Kumar, Arvind, Chakravarty, Sumana
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431446/
https://ncbi.nlm.nih.gov/pubmed/28473714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01297-z
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky