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Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
Krabbe disease (KD) is a neurodegenerative disorder caused by the lack of β- galactosylceramidase enzymatic activity and by widespread accumulation of the cytotoxic galactosyl-sphingosine in neuronal, myelinating and endothelial cells. Despite the wide use of Twitcher mice as experimental model for...
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| Publicado en: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431369/ https://ncbi.nlm.nih.gov/pubmed/28442746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-016-0001-8 |
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