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Cardioprotective effects of Cu((II))ATSM in human vascular smooth muscle cells and cardiomyocytes mediated by Nrf2 and DJ-1

Cu((II))ATSM was developed as a hypoxia sensitive positron emission tomography agent. Recent reports have highlighted the neuroprotective properties of Cu((II))ATSM, yet there are no reports that it confers cardioprotection. We demonstrate that Cu((II))ATSM activates the redox-sensitive transcriptio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Srivastava, Salil, Blower, Philip J., Aubdool, Aisah A., Hider, Robert C., Mann, Giovanni E., Siow, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431352/
https://ncbi.nlm.nih.gov/pubmed/28442712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-016-0012-5
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