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Interplay between CCN1 and Wnt5a in endothelial cells and pericytes determines the angiogenic outcome in a model of ischemic retinopathy

CYR61-CTGF-NOV (CCN)1 is a dynamically expressed extracellular matrix (ECM) protein with critical functions in cardiovascular development and tissue repair. Angiogenic endothelial cells (ECs) are a major cellular source of CCN1 which, once secreted, associates with the ECM and the cell surface and t...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Sangmi, Elaskandrany, Menna, Lau, Lester F., Lazzaro, Douglas, Grant, Maria B., Chaqour, Brahim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431199/
https://ncbi.nlm.nih.gov/pubmed/28469167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01585-8
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