The Matricellular Protein Cysteine-rich Protein 61 (CCN1/Cyr61) Enhances Physiological Adaptation of Retinal Vessels and Reduces Pathological Neovascularization Associated with Ischemic Retinopathy

Retinal vascular damages are the cardinal hallmarks of retinopathy of prematurity (ROP), a leading cause of vision impairment and blindness in childhood. Both angiogenesis and vasculogenesis are disrupted in the hyperoxia-induced vaso-obliteration phase, and recapitulated, although aberrantly, in th...

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Detalhes bibliográficos
Main Authors: Hasan, Adeel, Pokeza, Nataliya, Shaw, Lynn, Lee, Hyun-Seung, Lazzaro, Douglas, Chintala, Hemabindu, Rosenbaum, Daniel, Grant, Maria B., Chaqour, Brahim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3059032/
https://ncbi.nlm.nih.gov/pubmed/21212276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.198689
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