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The Matricellular Protein CCN1 (CYR61) Is Essential For Cardiac Development
The matricellular protein CCN1 (CYR61) regulates cell adhesion, migration, proliferation, survival, and differentiation through binding to integrin receptors and heparan sulfate proteoglycans. Here we show that Ccn1-null mice are impaired in cardiac valvulosepatal morphogenesis, resulting in severe...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1626492/ https://ncbi.nlm.nih.gov/pubmed/17023674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.RES.0000248426.35019.89 |
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