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Aspartate glycosylation triggers isomerization to isoaspartate
O-linked β-N-acetylglucosamine transferase (OGT) is an essential human enzyme that glycosylates numerous nuclear and cytoplasmic proteins on serine and threonine. It also cleaves Host cell factor 1 (HCF-1) by a mechanism in which the first step involves glycosylation on glutamate. Replacing glutamat...
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| Publicado en: | J Am Chem Soc |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5431074/ https://ncbi.nlm.nih.gov/pubmed/28207246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b12866 |
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