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Lentinan from shiitake selectively attenuates AIM2 and non-canonical inflammasome activation while inducing pro-inflammatory cytokine production

Lentinan extracted from shiitake (Lentinula edodes) is a β-glucan that has been reported as an intravenous anti-tumor polysaccharide via enhancement of the host immune system. In this study, we determined the effect of lentinan on inflammasome activation, a multi-protein platform, in myeloid cells....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ahn, Huijeong, Jeon, Eunsaem, Kim, Jin-Chul, Kang, Seung Goo, Yoon, Sung-il, Ko, Hyun-Jeong, Kim, Pyeung-Hyeun, Lee, Geun-Shik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5431005/
https://ncbi.nlm.nih.gov/pubmed/28465544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01462-4
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