A novel mechanism linking memory stem cells with innate immunity in protection against HIV-1 infection

HIV infection affects 37 million people and about 1.7 million are infected annually. Among the phase III clinical trials only the RV144 vaccine trial elicited significant protection against HIV-1 acquisition, but the efficacy and immune memory were inadequate. To boost these vaccine functions we stu...

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Publicado en:Sci Rep
Main Authors: Wang, Yufei, Whittall, Trevor, Neil, Stuart, Britton, Gary, Mistry, Mukesh, Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Kaewkungwal, Jaranit, Nitayaphan, Sorachai, Yu, Xuesong, Sato, Alicia, O’Connell, Robert J., Michael, Nelson L., Robb, Merlin L., Kim, Jerome H., Lehner, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430909/
https://ncbi.nlm.nih.gov/pubmed/28432326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01188-3
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