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Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c

UbcH5c belongs to the ubiquitin-conjugating enzyme family and plays an important role in catalyzing ubiquitination during TNF-α--triggered NF-κB activation. Therefore, UbcH5c is a potent therapeutic target for the treatment of inflammatory and autoimmune diseases induced by aberrant activation of NF...

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Foilsithe in:Acta Pharm Sin B
Main Authors: Wu, Fangshu, Zhu, Junsheng, Li, Honglin, Zhu, Lili
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430876/
https://ncbi.nlm.nih.gov/pubmed/28540177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.12.008
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