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Affinity biosensors using recombinant native membrane proteins displayed on exosomes: application to botulinum neurotoxin B receptor

The development of simple molecular assays with membrane protein receptors in a native conformation still represents a challenging task. Exosomes are extracellular vesicles which, due to their stability and small size, are suited for analysis in various assay formats. Here, we describe a novel appro...

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Publicado en:Sci Rep
Autores principales: Desplantes, Richard, Lévêque, Christian, Muller, Benjamin, Lotierzo, Manuela, Ferracci, Géraldine, Popoff, Michel, Seagar, Michael, Mamoun, Robert, El Far, Oussama
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430821/
https://ncbi.nlm.nih.gov/pubmed/28432329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01198-1
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