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Quiescence of adult oligodendrocyte precursor cells requires thyroid hormone and hypoxia to activate Runx1

The adult mammalian central nervous system (CNS) contains a population of slowly dividing oligodendrocyte precursor cells (OPCs), i.e., adult OPCs, which supply new oligodendrocytes throughout the life of animal. While adult OPCs develop from rapidly dividing perinatal OPCs, the mechanisms underlyin...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Tokumoto, Yasuhito, Tamaki, Shinpei, Kabe, Yasuaki, Takubo, Keiyo, Suematsu, Makoto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430791/
https://ncbi.nlm.nih.gov/pubmed/28432293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01023-9
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