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A Bimodal Influence of Thyroid Hormone on Cerebellum Oligodendrocyte Differentiation

Thyroid hormone (T(3)) can trigger a massive differentiation of cultured oligodendrocytes precursor cells (OPC) by binding the nuclear T(3) receptor α1 (TRα1). Whether this reflects a physiological function of TRα1 remains uncertain. Using a recently generated mouse model, in which CRE/loxP recombin...

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Detalles Bibliográficos
Publicado en:Mol Endocrinol
Main Authors: Picou, Frédéric, Fauquier, Teddy, Chatonnet, Fabrice, Flamant, Frédéric
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5417134/
https://ncbi.nlm.nih.gov/pubmed/22361821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1316
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