Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor α1 and krüppel-like factor 9 in Purkinje cells

Neurons in the CNS of higher vertebrates lose their ability to regenerate their axons at a stage of development that coincides with peak circulating thyroid hormone (T(3)) levels. Here, we examined whether this peak in T(3) is involved in the loss of axonal regenerative capacity in Purkinje cells (P...

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Autori principali: Avci, Hasan X., Lebrun, Clement, Wehrlé, Rosine, Doulazmi, Mohamed, Chatonnet, Fabrice, Morel, Marie-Pierre, Ema, Masatsugu, Vodjdani, Guilan, Sotelo, Constantino, Flamant, Frédéric, Dusart, Isabelle
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2012
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435228/
https://ncbi.nlm.nih.gov/pubmed/22891348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119853109
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