Thyroid hormone triggers the developmental loss of axonal regenerative capacity via thyroid hormone receptor α1 and krüppel-like factor 9 in Purkinje cells

Neurons in the CNS of higher vertebrates lose their ability to regenerate their axons at a stage of development that coincides with peak circulating thyroid hormone (T(3)) levels. Here, we examined whether this peak in T(3) is involved in the loss of axonal regenerative capacity in Purkinje cells (P...

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Main Authors: Avci, Hasan X., Lebrun, Clement, Wehrlé, Rosine, Doulazmi, Mohamed, Chatonnet, Fabrice, Morel, Marie-Pierre, Ema, Masatsugu, Vodjdani, Guilan, Sotelo, Constantino, Flamant, Frédéric, Dusart, Isabelle
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435228/
https://ncbi.nlm.nih.gov/pubmed/22891348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119853109
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