Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress

Mycothiol (MSH) is the major low molecular weight (LMW) thiol in Actinomycetes. Here, we used shotgun proteomics, OxICAT and RNA-seq transcriptomics to analyse protein S-mycothiolation, reversible thiol-oxidations and their impact on gene expression in Mycobacterium smegmatis under hypochlorite stre...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hillion, Melanie, Bernhardt, Jörg, Busche, Tobias, Rossius, Martina, Maaß, Sandra, Becher, Dörte, Rawat, Mamta, Wirtz, Markus, Hell, Rüdiger, Rückert, Christian, Kalinowski, Jörn, Antelmann, Haike
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430705/
https://ncbi.nlm.nih.gov/pubmed/28446771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01179-4
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