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Transcriptomic analysis reveals a previously unknown role for CD8(+) T-cells in rVSV-EBOV mediated protection

Ebola virus (EBOV) poses a significant threat to human health as highlighted by the recent epidemic in West Africa. Data from animal studies and a ring vaccination clinical trial conducted in Guinea during the recent epidemic demonstrated that a recombinant VSV where G protein is replaced with EBOV...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Menicucci, Andrea R., Sureshchandra, Suhas, Marzi, Andrea, Feldmann, Heinz, Messaoudi, Ilhem
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430516/
https://ncbi.nlm.nih.gov/pubmed/28428619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-01032-8
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