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Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration

We present a novel, all-electric approach to record and to precisely control the activity of tens of individual presynaptic neurons. The method allows for parallel mapping of the efficacy of multiple synapses and of the resulting dynamics of postsynaptic neurons in a cortical culture. For the measur...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jäckel, David, Bakkum, Douglas J., Russell, Thomas L., Müller, Jan, Radivojevic, Milos, Frey, Urs, Franke, Felix, Hierlemann, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430511/
https://ncbi.nlm.nih.gov/pubmed/28428560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00981-4
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