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Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration

We present a novel, all-electric approach to record and to precisely control the activity of tens of individual presynaptic neurons. The method allows for parallel mapping of the efficacy of multiple synapses and of the resulting dynamics of postsynaptic neurons in a cortical culture. For the measur...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Jäckel, David, Bakkum, Douglas J., Russell, Thomas L., Müller, Jan, Radivojevic, Milos, Frey, Urs, Franke, Felix, Hierlemann, Andreas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430511/
https://ncbi.nlm.nih.gov/pubmed/28428560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00981-4
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