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Combination of High-density Microelectrode Array and Patch Clamp Recordings to Enable Studies of Multisynaptic Integration

We present a novel, all-electric approach to record and to precisely control the activity of tens of individual presynaptic neurons. The method allows for parallel mapping of the efficacy of multiple synapses and of the resulting dynamics of postsynaptic neurons in a cortical culture. For the measur...

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書目詳細資料
發表在:Sci Rep
Main Authors: Jäckel, David, Bakkum, Douglas J., Russell, Thomas L., Müller, Jan, Radivojevic, Milos, Frey, Urs, Franke, Felix, Hierlemann, Andreas
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5430511/
https://ncbi.nlm.nih.gov/pubmed/28428560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00981-4
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