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Similarity- and Substructure-Based Development of β(2)-Adrenergic Receptor Ligands Based on Unusual Scaffolds
[Image: see text] The β(2)-adrenergic receptor (β(2)AR) is a G protein-coupled receptor (GPCR) and a well-explored target. Here, we report the discovery of 13 ligands, ten of which are novel, of this particular GPCR. They have been identified by similarity- and substructure-based searches using mult...
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| 發表在: | ACS Med Chem Lett |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical
Society
2017
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5430404/ https://ncbi.nlm.nih.gov/pubmed/28523097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00363 |
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